منابع مشابه
P 133: Neuroinflammation in Alzheimer ’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia. Almost 47 million people suffer from dementia worldwide. AD accounts for approximately 60%–80% of all dementia cases. Three major pathologies characterize the disease: senile plaques, neurofibrillary tangles and inflammation. We review the literature on events contributing to the inflammat...
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As the population ages, Alzheimer disease is becoming more of a medical, social and public health concern. It is a dementing disorder that causes severe and permanent loss of intellectual function. Patients with Alzheimer disease begin having forgetfulness, then progress to having irreversible loss of memory (including the memory of their own families) and other previously well-learned skills. ...
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(a) The types of population vary enormously in parameters such as place of residence (e.g. community versus hospital-based samples) and age range (as dementia is much more common in the very elderly, a sample stratified towards the upper age ranges will contain numerically more cases). (b) The diagnostic procedures vary, some involve personal examination by trained staff, others rely on second-...
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Informative genetic testing is currently available to only a small number of families with a history of early-onset (younger than 60 years of age) Alzheimer disease (AD). For these families, the benefits of genetic testing are limited and are mainly related to the individual’s perception of the psychological advantages of knowing whether or not he or she is predisposed to develop AD. There rema...
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ژورنال
عنوان ژورنال: Prion
سال: 2013
ISSN: 1933-6896,1933-690X
DOI: 10.4161/pri.22118